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September 25, 2026International MicrobiologyOpen Access

A microbiota–substrate–metabolite–target network suggests AKT1-associated links between gut microbiota-derived metabolites and osteoporosis

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Authors

WZWenxing ZengYGYuan GongYLYitao Liao

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Zeng et al. (2026) studied this question.

synapsesocial.com/papers/6ab60fd1406bf401c1468aa5https://doi.org/10.1007/s10123-026-00899-w
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrated transcriptomic analysis identifies an AKT1-associated metabolic-inflammatory signature in osteoporosis2026
  2. 2Genome-Resolved Functional Profiling of Osteoporosis-Associated Gut Bacteria Highlights Putative Metabolic and Immunogenic Signatures of the Gut–Bone Axis2026
  3. 3Methyl-4-hydroxybenzoate induces osteoporosis via the AKT1/LC3B/Beclin1 autophagy signaling pathway: Integrating network toxicology and experimental validation2026
  4. 4The gut microbiota in osteoporosis: dual roles and therapeutic prospects2025 · 19 citations
  5. 5Integrated Multi-Omics Identification of Novel Diagnostic Biomarkers andImmunometabolic Therapeutic Targets in Osteoporosis via MachineLearning2026