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An active probe and microstimulator SoC for interfacing with peripheral nerves is presented. It performs 64-channel artifact-tolerant neural recording, cuff imbalance compensation by impedance sensing, and neurostimulation for the closed-loop operation. Each recording channel is a second-order opamp-lessΔ ΣADC that consumes 140 nW and occupies 0.01 mm2area in 130 nm CMOS. The single-loopΔ Σarchitecture achieves second-order noise shaping with two passive integrators. To the best of our knowledge, this yields the lowest power and area of any second-orderΔ ΣADC and the lowest FOM (fJ/conv. step) of any passive second-orderΔ ΣADC (27 fJ/conv. step). The SoC uniquely performs multi-modal input signal recording: voltage (for neural recording) and current (for impedance sensing) are measured concurrently using frequency multiplexing. The SoC also features a 60 MHz energy-efficient inductive powering link and a 600 MHz RF data communication link. The prototype is validatedin vivoin the rat sciatic nerve for electroneurogram (ENG) sensing and the correction of impedance-imbalance in cuff electrodes.
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ElAnsary et al. (2021) studied this question.
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