Key result
Very late stent thrombosis occurs 26 months after SES implantation despite uninterrupted DAPT.
Why the study?
Very late stent thrombosis after drug-eluting stent implantation is a rare but fatal complication even in patients without aspirin and clopidogrel resistance.
Case Report (n=1)
No
Demonstrates that very late stent thrombosis can occur after drug-eluting stent implantation despite continued dual antiplatelet therapy and absence of anti-platelet resistance.
VLST can occur on DAPT without resistance; leaves open mechanisms beyond platelet reactivity in sirolimus-eluting stents.
Very Late Stent Thrombosis after Drug-Eluting Stent Implantation in a Patient without Aspirin and Clopidogrel ResistanceVery late stent thrombosis (VLST) after implantation of drug-eluting stent is rare, but very fatal complication after percutaneous coronary intervention.We report a case of VLST of a sirolimus-eluting Cypher TM stent (Cordis, Johnson and Johnson) presenting as acute ST elevation myocardial infarction at 26 months after deployment with continued combined dual antiplatelet medication of aspirin and clopidogrel.The patient did not show anti-platelet resistance.
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Lim et al. (2008) conducted a case report in Very late stent thrombosis (n=1). Sirolimus-eluting stent and dual antiplatelet therapy was evaluated on Very late stent thrombosis. Very late stent thrombosis occurred 26 months after sirolimus-eluting stent implantation despite continued dual antiplatelet therapy and confirmed absence of aspirin and clopidogrel resistance.
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