Key result
Paclitaxel DES linked to acute STEMI from extremely late in-stent thrombosis after 12 years.
Why the study?
Stent thrombosis typically occurs within days after stent deployment and becomes extremely rare once the stent is endothelialized, with very late cases reported up to 11 years.
Case Report (n=1)
No
This case report highlights the rare possibility of extremely late stent thrombosis occurring up to 12 years after drug-eluting stent implantation.
Very late stent thrombosis may occur beyond 11 years; extends known timelines but leaves open questions on lifelong risk and antiplatelet duration.
Stent thrombosis is one of the most feared complications of percutaneous coronary intervention. Most commonly it occurs within the first few days after the deployment of the stent. Once the stent is completely endothelialized, this complication becomes extremely rare. Few cases of very late stent thrombosis were reported in the literature with the longest interval being around 11 years after the initial intervention. We report here the case of a 78-year-old male patient who presented with acute onset chest pain found to have acute inferior ST-segment elevation myocardial infarction due to thrombotic occlusion of a prior paclitaxel drug-eluting stent placed 12 years prior. This is, to our knowledge, the first case of stent thrombosis occurring after this long duration since stent implantation.
No takes yet. Share an insight, caveat, or question.
Sleiman et al. (2020) conducted a case report in Extremely late in-stent thrombosis (n=1). Paclitaxel drug-eluting stent was evaluated on Stent thrombosis. A 78-year-old man developed an acute inferior STEMI due to extremely late in-stent thrombosis 12 years after receiving a paclitaxel drug-eluting stent, the longest interval reported to date.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: