Key result
Alcohol use linked to ~50% higher rate of antihypertensive dose up-titration in men.
Why the study?
Alcohol consumption is a proven risk factor of hypertension, but its impact on antihypertensive treatment and blood pressure control in male hypertensive patients was investigated.
Does alcohol consumption increase the required dosage of antihypertensive medications to achieve blood pressure control in male patients with hypertension?
Cohort (n=236)
Does alcohol consumption increase the required dosage of antihypertensive medications to achieve blood pressure control in male patients with hypertension?
Absolute Event Rate: 54.7% vs 36.6%
p-value: p=0.01
Male alcohol drinkers with hypertension require higher dosages of antihypertensive medications to achieve similar blood pressure control compared to non-drinkers.
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May warrant alcohol assessment during antihypertensive titration in men; leaves open causality and need for prospective confirmation.
Ye et al. (2023) conducted a cohort in Hypertension (n=236). Alcohol consumption vs. Non-drinkers was evaluated on Use of higher dosages of antihypertensive drugs at 12 weeks of follow-up (p=0.01). Male alcohol drinkers with hypertension required a significantly higher rate of up-titrated antihypertensive dosages at 12 weeks compared to non-drinkers (54.7% vs. 36.6%, P=0.01).
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