Key result
SMI shows good consistency with CEUS for carotid intraplaque neovascularization, with ~0.74 pooled kappa.
Why the study?
The consistency between superb microvascular imaging and contrast-enhanced ultrasonography in detecting intraplaque neovascularization was unclear.
Does superb microvascular imaging (SMI) show consistency with contrast-enhanced ultrasonography (CEUS) in detecting intraplaque neovascularization in carotid plaques?
Meta-Analysis (n=608)
Does superb microvascular imaging (SMI) show consistency with contrast-enhanced ultrasonography (CEUS) in detecting intraplaque neovascularization in carotid plaques?
Superb microvascular imaging demonstrates good consistency with contrast-enhanced ultrasonography for detecting carotid intraplaque neovascularization, suggesting it may be a viable alternative.
Supports superb microvascular imaging as a contrast-free option for carotid plaque assessment; reinforces diagnostic consistency with contrast-enhanced ultrasonography.
This meta-analysis aimed to identify the consistency of superb microvascular imaging(SMI) and contrast-enhanced ultrasonography(CEUS) in detecting intraplaque neovascularization(IPN). We searched PubMed, Web of Science, Cochrane Library, CISCOM, and CBM databases without language restrictions. Meta-analysis was conducted using STATA version 15.1 software. We calculated the pooled Kappa index. Ten studies that met all inclusion criteria were included in this meta-analysis. A total of 608 carotid plaques were assessed through both SMI and CEUS. The pooled summary Kappa index was 0.743(95 % CI=0.696-0.790) with statistical significance(z= 31.14, p<0.01). We found no evidence for publication bias (t=-1.21, p=0.261). Our meta-analysis indicates that SMI and CEUS display a good consistency in detecting IPN of carotid plaque, that is to say SMI ultrasound maybe a promising alternative to CEUS for detecting IPN of carotid plaque.
No takes yet. Share an insight, caveat, or question.
Yang et al. (2020) conducted a meta-analysis in Carotid plaque (intraplaque neovascularization) (n=608). Superb microvascular imaging (SMI) vs. Contrast-enhanced ultrasonography (CEUS) was evaluated on Consistency in detecting intraplaque neovascularization (pooled Kappa index) (Kappa index 0.743, 95% CI 0.696-0.790, p=<0.01). Superb microvascular imaging demonstrated good consistency with contrast-enhanced ultrasonography in detecting intraplaque neovascularization of carotid plaques (pooled Kappa index 0.743).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: