Key result
MitraClip enables transcatheter edge-to-edge repair for severe common atrioventricular valve regurgitation in single ventricle anatomy.
Why the study?
Atrioventricular valve regurgitation in single ventricle patients with unbalanced atrioventricular septal defects is associated with poor outcomes and often requires surgical treatment.
Case Report (n=1)
Demonstrates the potential feasibility of transcatheter edge-to-edge repair for severe common AVVR in a complex congenital heart disease patient with single ventricle physiology.
May support MitraClip feasibility in single-ventricle AVVR; hypothesis-generating and requires prospective validation before adoption.
Congenital heart disease patients, specifically with unbalanced atrioventricular septal defects and common atrioventricular valves requiring single ventricle palliation, have substantial morbidity and mortality. Atrioventricular valve regurgitation (AVVR) is associated with poor outcomes in single ventricle patients, and many of them require surgical treatment of AVVR in their lifetimes. We describe a unique case of transcatheter edge-to-edge valve repair using the MitraClip system (Abbott, Chicago, IL) in a single ventricle patient with severe common AVVR.
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Tan et al. (2020) conducted a case report in Heterotaxy syndrome, single ventricle physiology, unbalanced atrioventricular septal defect, severe common atrioventricular valve regurgitation (n=1). Transcatheter edge-to-edge valve repair using the MitraClip system was evaluated. Transcatheter edge-to-edge valve repair using the MitraClip system was described in a single ventricle patient with severe common atrioventricular valve regurgitation.
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