Key result
Excised human myocardium shows ~1.3% ultrasonic velocity anisotropy, peaking along muscle fibers.
Why the study?
The anisotropy of ultrasonic velocity and elastic properties in normal human myocardium was characterized to understand transmural dependence and fiber orientation effects.
This study demonstrates a 1.3% anisotropy in ultrasonic velocity in normal human myocardium, which correlates with myofiber orientation and allows estimation of tissue elastic constants.
Answers are grounded in this paper and cite their sources.
Ex vivo anisotropy data warrant caution assuming isotropic myocardial ultrasound properties; leaves open translation to in vivo imaging or elastography.
Measurements of ultrasonic quasilongitudinal velocity were made in the muscle fiber plane of excised human myocardium. Multiple adjacent planes across the left ventricular wall were interrogated to assess the transmural dependence of velocity. For each measurement plane, data were obtained in 2-deg increments through the full 360 deg relative to the myofibers. An approximate 1.3% magnitude of anisotropy was observed with maximum velocity along the muscle fibers and minimum velocity perpendicular to the muscle fibers. The known transmural shift in myofiber orientation was evidenced in the anisotropy of velocity as angular shifts between plots obtained from adjacent transmural planes within the same specimen. Measured values of velocity and density were used to estimate the effective C33 and C11 elastic constants of a thin layer of normal myocardium.
No takes yet. Share an insight, caveat, or question.
Verdonk et al. (1992) studied Normal human myocardium. Ultrasonic quasilongitudinal velocity measurement was evaluated on Anisotropy of ultrasonic velocity. Ultrasonic quasilongitudinal velocity measurements in excised normal human myocardium demonstrated an approximate 1.3% magnitude of anisotropy, with maximum velocity along the muscle fibers.
Synapse has enriched 10 related papers. Consider them for comparative context: