Key result
Sequencing of 13 PCV1 strains from piglets in China revealed high nucleotide similarity, one putative recombinant strain (GXdx84), and a novel cap gene mutation in strain GXyl224 that lengthened the gene sequence.
The study identifies genetic variations and a novel recombinant strain of PCV1 in Chinese piglets, contributing to the understanding of its evolution and molecular epidemiology.
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May warrant PCV1 surveillance in swine; leaves open extent of genetic variation and clinical relevance.
Cao et al. (2018) studied Porcine circovirus type 1 (PCV1) infection (n=247). Whole-genome sequencing of PCV1 vs. Reference strains was evaluated on Genetic variation and phylogenetic analysis of PCV1 strains. Sequencing of 13 PCV1 strains from piglets in China revealed high nucleotide similarity, one putative recombinant strain (GXdx84), and a novel cap gene mutation in strain GXyl224 that lengthened the gene sequence.