New and not so new vaccines

severe hypoglycaemia over a period of between five and 15 years is either mild or negligible.For a few individuals, with vulnerability factors which as yet remain obscure, brain function may be permanently and importantly affected.Strict gly- caemic control has the great benefit of reducing target organ damage-delaying the onset and slowing the progress of retin- opathy, nephropathy, and neuropathy-but brings with it a threefold increase in severe hypoglycaemia."2No one doubts that severe hypoglycaemia should be avoided, but patients and their carers are right in demanding more research to help them make intelligent decisions about the long term trade off between the Scylla of hyperglycaemia and the possible Charybdis of hypoglycaemia.