Key result
Antioxidants show potential as supportive CHD therapy by reducing LDL oxidation and arterial hardening.
Why the study?
Coronary heart disease remains a major problem worldwide with oxidative stress playing a key role in its pathophysiology, and the potential benefit of antioxidants in treatment is of interest.
This narrative review highlights the potential of antioxidants as an adjunctive non-pharmacological therapy to reduce oxidative stress and inhibit atherosclerosis in coronary heart disease.
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Mitochondrial oxidative stress in CHD pathophysiology remains hypothesis-generating; prospective trials needed before clinical translation.
Santosa et al. (2020) conducted a review in Coronary heart disease. Antioxidants was evaluated. Antioxidants have the potential to serve as supportive therapy for coronary heart disease by reducing LDL oxidation and inhibiting arterial hardening.
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