Answers are grounded in this paper and cite their sources.
Cascading reactions, including the conversion of a TMS-epoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.
No takes yet. Share an insight, caveat, or question.
Nicolaou et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: