Key result
Older age and higher BMI are independently linked to left atrial enlargement in newly diagnosed DM2.
Why the study?
Duration of type 2 diabetes mellitus has been associated with increased left atrial volume and impaired function, but changes at six months disease duration are unclear.
What are the changes in left atrial volume and function in patients with type 2 diabetes mellitus with a disease duration of six months?
Cross-Sectional
What are the changes in left atrial volume and function in patients with type 2 diabetes mellitus with a disease duration of six months?
In patients with newly diagnosed type 2 diabetes, impaired left atrial function may be present, with age and BMI independently driving LA enlargement.
LA changes may emerge early in DM2; leaves open prognostic value and need for longitudinal confirmation.
INTRODUCTION: Changes in left atrial (LA) size and function are associated with adverse clinical events. Recently, duration of diabetes mellitus (DM2) has been found to be positively associated with increased LA volume and impaired LA function. This study was performed, using two-dimensional echocardiograpy, to evaluate the changes in LA volume and function in patients with DM2 with a disease duration of six months, and to assess the parameters that affect LA volume and function. METHODS: ) and LA function [passive emptying volume - passive emptying fraction (PEV - PEF), active emptying volume - active emptying fraction (AEV - AEF), total emptying volume - total emptying fraction (TEV - TEF) ]. RESULTS: level, body mass index (BMI), high-sensitivity C-reactive protein and uric acid levels, mitral A wave, E/E' ratio and A' wave. According to multivariate analysis, age and BMI had a statistically significant effect on LA volume. CONCLUSION: Impaired LA function may be present in patients with newly diagnosed DM2. BMI and increasing age caused LA enlargement and LA volumes that were independent of the effects of hypertension and DM2.
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Gülmez et al. (2018) conducted a cross-sectional in Type 2 diabetes mellitus. Type 2 diabetes mellitus (6 months duration) was evaluated on Left atrial volume and function. In patients with newly diagnosed type 2 diabetes mellitus, increasing age and body mass index were significantly associated with left atrial enlargement, independent of hypertension and DM2.
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