Key result
A case of profound hypotension and shock due to amlodipine overdose was successfully managed with early aggressive supportive measures and large doses of calcium infusion.
Case Report (n=1)
Amlodipine overdose can cause profound shock, which can be successfully managed with aggressive supportive care and high-dose calcium infusion.
May support high-dose calcium in amlodipine shock; single case leaves open need for controlled trials.
Amlodipine is a commonly prescribed calcium channel blocker. Its toxicity is the leading cause of drug overdose seen in the practice of cardiovascular medicine. It can lead to profound hypotension and shock. Management involves early and aggressive supportive measures and calcium infusion in large doses to overcome competitive blockade. We report one such case that presented with amlodipine overdose and was successfully managed.
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Handa et al. (2013) conducted a case report in Amlodipine overdose and shock (n=1). Supportive measures and calcium infusion was evaluated on Successful management. A case of profound hypotension and shock due to amlodipine overdose was successfully managed with early aggressive supportive measures and large doses of calcium infusion.
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