Key result
Pericardiocentesis with surgical fenestration successfully resolves acute tamponade in pericardial mesothelioma.
Why the study?
Malignant pericardial effusion is a frequent complication in mediastinal and pleural malignancies but is rarely the first manifestation of a malignant tumour presenting as cardiac tamponade.
Case Report (n=1)
Highlights that life-threatening cardiac tamponade can be a rare first manifestation of pericardial mesothelioma, which can be acutely managed with pericardiocentesis.
May warrant considering pericardial mesothelioma in unexplained tamponade; single-case evidence leaves broader recommendations open.
Malignant pericardial effusion is a frequent complication in primary mediastinal and pleural malignancies. As a first manifestation of a malignant tumour, however, it is rare. With cardiac tamponade the likelihood of malignancy increases. We report a life-threatening cardiac tamponade as the primary clinical presentation of a pericardial mesothelioma. Pericardiocentesis resolved the acute symptoms, followed by surgical pericardial fenestration. Oncologic therapy is evidently indicated. All mesotheliomas carry a poor prognosis.
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Ceuninck et al. (2013) conducted a case report in Malignant cardiac tamponade due to pericardial mesothelioma (n=1). Pericardiocentesis and surgical pericardial fenestration was evaluated on Resolution of acute symptoms. Pericardiocentesis followed by surgical pericardial fenestration successfully resolved acute symptoms in a patient presenting with life-threatening cardiac tamponade due to pericardial mesothelioma.
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