Key result
Balloon pulmonary valvuloplasty fails in ~20% of pediatric patients, with similar rates across age groups.
Why the study?
Characteristics and outcomes of pulmonary valve balloon valvuloplasty in children under 15 years were not well compared across different age groups.
Do outcomes of pulmonary valve balloon valvuloplasty differ across childhood age groups in children under 15 years of age with pulmonary stenosis?
Cohort
No
Do outcomes of pulmonary valve balloon valvuloplasty differ across childhood age groups in children under 15 years of age with pulmonary stenosis?
Percutaneous pulmonary valve balloon valvuloplasty in children has a failure rate of nearly 20%, with no significant difference in outcomes across childhood age groups.
High failure rate without age differences in this cohort advises procedural caution in children; leaves open need for prospective trials on selection and techniques.
The aim of this study was to investigate the characteristics and outcomes of treating pulmonary stenosis with percutaneous valvuloplasty, and to compare them among three childhood age groups. All children under 15 years of age who had undergone pulmonary valve balloon valvuloplasty in Madani Heart Center from 2005-2009 were enrolled in this study. Data were analyzed using IBM SPSS software (SPSS, Inc, Chicago, IL). Mean (± standard deviation) age of patients was 55.5 ± 47.4 months. Two-thirds of the subjects had moderate pulmonary valve stenosis. Balloon valvuloplasty failed in nearly one-fifth of the treated patients. There were 17 failures and two cases of mortality, descriptively less frequent among children >5 years; however, the observed difference was not statistically significant. Mild pulmonary valve insufficiency was a common finding.
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Ghaffari et al. (2012) conducted a cohort in Pulmonary stenosis. Pulmonary valve balloon valvuloplasty vs. Different age groups was evaluated on Failure and mortality. Pulmonary valve balloon valvuloplasty for pulmonary stenosis failed in nearly one-fifth of patients (17 failures, 2 deaths), with no statistically significant difference across age groups.
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