Key result
Patients with GERD had significantly higher psychosomatic evaluation scores compared to controls (p < 0.001), and baseline GERDQ ≥10 and SSS-8 ≥12 predicted refractory GERD (p=0.004 and p=0.009).
Why the study?
Do psychosomatic evaluations and heart rate variability correlate with GERD and predict refractory GERD in patients with reflux esophagitis treated with PPIs?
Population
105 individuals with reflux esophagitis and a control group of 50 participants without acid reflux symptoms
Comparison
Proton pump inhibitor administered regularly for… vs 50 participants without acid reflux symptoms
Design
Cohort
Follow-up
8 weeks
Authors
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High baseline GERDQ and SSS-8 scores were associated with PPI-refractory GERD; leaves open whether psychosomatic screening improves outcomes in prospective trials.
Cohort (n=155)
Do psychosomatic evaluations and heart rate variability correlate with GERD and predict refractory GERD in patients with reflux esophagitis treated with PPIs?
p-value: p=< 0.001
Higher baseline psychosomatic symptom scores predict refractory GERD after 8 weeks of PPI treatment, highlighting the importance of integrating psychological assessments and stress management into GERD care.
Wang et al. (2023) conducted a cohort in Gastroesophageal reflux disease (GERD) (n=155). Gastroesophageal reflux disease (GERD) vs. Participants without acid reflux symptoms was evaluated on Psychosomatic evaluations (GERDQ, GERDQLQ, RSI, BAI, BDI, and SSS-8) (p=< 0.001). Patients with GERD had significantly higher psychosomatic evaluation scores compared to controls (p < 0.001), and baseline GERDQ ≥10 and SSS-8 ≥12 predicted refractory GERD (p=0.004 and p=0.009).
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