Key result
Axillobifemoral grafts are linked to ~60% higher 5-year patency than axillounifemoral bypass in limb salvage.
Why the study?
Axillofemoral bypass is used as a limb salvage procedure in patients with severe limb ischaemia considered unfit for major aortic reconstruction, but outcomes and graft patency data are needed.
Does axillofemoral bypass provide effective limb salvage in high-risk patients with severe limb ischaemia unfit for major aortic reconstruction?
Comparison
Axillounifemoral grafts vs axillobifemoral grafts
Design
Cohort study
Follow-up
5 years
Authors
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Acceptable limb salvage supports axillofemoral bypass in unfit patients; leaves open need for prospective comparison with endovascular options.
Cohort (n=38)
Does axillofemoral bypass provide effective limb salvage in high-risk patients with severe limb ischaemia unfit for major aortic reconstruction?
Absolute Event Rate: 80% vs 50%
p-value: p=<0.05
Axillofemoral bypass is a viable limb salvage option with acceptable 5-year patency and limb salvage rates for high-risk patients unfit for major aortic reconstruction, with axillobifemoral grafts showing superior patency to unifemoral grafts.
Naylor et al. (1990) conducted a cohort in Severe limb ischaemia and aortoiliac disease (n=38). Axillobifemoral grafts vs. Axillounifemoral grafts was evaluated on 5-year patency (p=<0.05). Axillobifemoral grafts demonstrated significantly better 5-year patency compared to axillounifemoral grafts (80% vs 50%, P<0.05) in high-risk patients undergoing limb salvage for severe ischaemia.
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