Key result
TAVI-TEC AI matches clinician annular measurements and predicts prosthesis size with ~82% accuracy.
Why the study?
Improving efficiency and standardizing annotations in preprocedural TAVI planning using CTA is essential as TAVI procedure volume increases.
Does the TAVI-TEC AI-based tool provide accurate pre-procedural anatomical measurements and valve size prediction compared to manual clinician assessment in patients with severe aortic stenosis undergoing TAVI?
Observational (n=109)
No
Does the TAVI-TEC AI-based tool provide accurate pre-procedural anatomical measurements and valve size prediction compared to manual clinician assessment in patients with severe aortic stenosis undergoing TAVI?
Effect estimate: CCC = 0.934
The TAVI-TEC AI tool provides rapid, automated, and accurate pre-procedural anatomical measurements and valve sizing for TAVI, potentially streamlining clinical workflows and reducing operator variability.
May streamline TAVI planning efficiency; leaves open need for prospective validation before clinical use.
Computed tomography angiography (CTA) is crucial for preprocedural TAVI planning, providing the anatomical information required for prosthesis sizing and vascular access assessment. As the volume of TAVI procedure increases, improving efficiency and standardizing annotations is becoming essential in clinical practice. This study presents TAVI-TEC, a fully automated artificial intelligence-based framework integrated into a web based DICOM viewer for routine preoperative TAVI planning. Pre-procedural CTA scans from patients undergoing TAVI with SAPIEN 3 Ultra (S3U) prostheses were processed using a fully automated pipeline. Deep learning-based segmentation of cardiovascular structures, calcification detection, centerline extraction, landmark identification, and annular plane definition was implemented to quantify key annular and aortic root measurements and color-coded maps of lumen reduction and vessel diameter for vascular access. A multilayer perceptron classifier was trained to predict prosthesis size prior to the TAVI procedure. Results revealed that TAVI-TEC enabled pre-procedural measurements in approximately 2-6 min. Strong agreement with clinician-derived measurements was observed for annular area (coefficient of concordance, CCC = 0.934; interclass correlation coefficient, ICC = 0.935; R^2 = 0.881) and perimeter (CCC = 0.909; ICC = 0.909; R^2 = 0.854). The valve-size prediction model achieved 82% overall accuracy, with most misclassifications occurring between adjacent prosthesis sizes. Though further multicenter validation and extension to additional measurements and valve platforms are required, the TAVI-TEC methodology may reduce operator variability in pre-TAVI measurements and streamline the preoperative workflows of the Heart Team for decision-making.
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Zerillo et al. (2026) conducted an observational in Severe aortic stenosis (n=109). TAVI-TEC AI-based tool vs. Clinician-derived manual measurements was evaluated on Agreement with clinician-derived measurements for annular area (CCC = 0.934). The TAVI-TEC AI-based tool demonstrated strong agreement with clinician-derived measurements for annular area (CCC = 0.934) and achieved 82% overall accuracy in predicting prosthesis size.
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