Key result
Acquired triggers can unmask a Type 1 Brugada ECG pattern mimicking acute coronary syndrome.
Why the study?
A Type 1 Brugada ECG pattern may mimic acute coronary syndrome, requiring careful assessment to distinguish it from true Brugada syndrome or phenocopy.
Case Report (n=1)
No
Highlights the importance of distinguishing a Type 1 Brugada ECG pattern from acute coronary syndrome and identifying potential acquired triggers before diagnosing Brugada syndrome.
Alerts clinicians to acquired mimics before diagnosing Brugada syndrome in ACS-like ECGs; leaves diagnostic criteria and testing thresholds open.
A Type 1 Brugada ECG pattern may mimic acute coronary syndrome. Careful assessment of cardiac biomarkers, electrolyte abnormalities, medications, and possible substance exposure is essential. Without follow-up ECG, provocative testing, or genetic evaluation, the finding should be described cautiously as a Brugada-pattern ECG rather than confirmed Brugada syndrome or phenocopy.
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Ghadeer Doman (2026) conducted a case report in Type 1 Brugada ECG pattern mimicking acute coronary syndrome (n=1). Multiple potential acquired contributors (hyponatremia, renal dysfunction, possible cocaine use, remote COVID-19) was evaluated on Diagnosis and etiology of Type 1 Brugada ECG pattern. A Type 1 Brugada ECG pattern mimicking acute coronary syndrome was identified in a patient with multiple potential acquired contributors, highlighting the need for careful assessment and follow-up.
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