Microwave assisted synthesis of naphtho[2,1-b]furan-1, 3, 4-benzotriazepines: a potent antimicrobial agent

Synthesis of 3-{naphtho[2,1-b]furan-2-ylcarbonyl}-3H-1,3,4-benzotriazepine 6 was reported.The conversion of 3 into various substituted derivatives of schiff bases by reacting with substituted 2-aminobenzaldehyde 4, which intern cyclise in presence of triethyl ortho formate to produce the title compounds.The structures of all the newly synthesized compounds have been established by 1 H NMR, IR, Mass spectra and elemental analysis.The selected compounds have been screened for antibacterial and antifungal activities.