Key result
Pacemakers are essential for symptomatic bradycardia, and pacing modes maintaining atrioventricular synchrony reduce atrial fibrillation, while cardiac resynchronization improves survival in heart failure.
Why the study?
Pacemakers are the only treatment for symptomatic bradycardia not due to reversible causes, but optimal use and follow-up require clarification.
This review summarizes the contemporary indications and benefits of pacemakers and cardiac resynchronization therapy for bradycardia and heart failure.
Pacemakers remain sole therapy for symptomatic bradycardia; review extends RCT data but leaves optimal follow-up open.
Implantable cardiac devices have become firmly entrenched as important therapeutic tools for a variety of cardiac conditions. The first part of this two-part review will discuss the contemporary use and follow-up of pacemakers, while the second part will address the use of implantable cardioverter defibrillators and implantable loop recorders. Pacemakers are the only available treatment for symptomatic bradycardia not due to reversible causes. Large randomized studies have demonstrated a small but statistically significant reduction in atrial fibrillation associated with pacing modes that maintain atrioventricular synchrony. In contrast, pacing mode appears to have a less dramatic effect in patients with atrioventricular block. Cardiac resynchronization with specialized left ventricular leads has been shown to reduce symptoms and improve survival in patients with symptomatic heart failure, systolic dysfunction, and widened QRS complexes. For all patients, careful follow-up is necessary to ensure optimal therapeutic benefit of pacing systems.
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Kusumoto et al. (2006) conducted a review in Cardiac conditions requiring pacemakers. Pacemakers was evaluated. Pacemakers are essential for symptomatic bradycardia, and pacing modes maintaining atrioventricular synchrony reduce atrial fibrillation, while cardiac resynchronization improves survival in heart failure.
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