Key result
Green tea, sage, and ginseng lower glucose and improve lipids in diabetic rats, led by ginseng.
Why the study?
The effect of aqueous extracts from green tea, sage, and ginseng on insulin sensitivity and glucose metabolism in alloxan-induced diabetic rats was unclear.
Do aqueous extracts of green tea, sage, or ginseng improve insulin sensitivity and metabolic parameters in alloxan-diabetic rats?
Population
24 normal and 24 alloxan-diabetic male albino rats
Comparison
Aqueous extracts of green tea, sage, or ginseng vs untreated controls
Authors
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Should not change practice; hypothesis-generating for antidiabetic effects of ginseng, sage, and green tea extracts in humans.
Do aqueous extracts of green tea, sage, or ginseng improve insulin sensitivity and metabolic parameters in alloxan-diabetic rats?
p-value: p=<0.05
Aqueous extracts of green tea, sage, and especially ginseng improve glycemic control, lipid profiles, and liver enzymes in a rat model of diabetes.
Gehan S. Moram (2001) studied Alloxan-induced diabetes (n=48). Aqueous extracts from green tea, sage, and ginseng panax vs. Untreated diabetic and normal control groups was evaluated on Blood glucose, plasma insulin, serum lipids, liver glycogen, and glucose metabolism enzymes (p=<0.05). Aqueous extracts of green tea, sage, and ginseng significantly decreased blood glucose (p<0.05) and improved insulin, glycogen, and lipid profiles in diabetic rats, with ginseng being the most efficient.
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