Key result
Gore Septal Occluder successfully achieves complete transcatheter native aortic valve closure in severe AR.
Why the study?
Semilunar valve regurgitation in single ventricular physiology is rare and medical therapy is often ineffective, with surgical repair or replacement associated with poor outcomes.
Does transcatheter native aortic valve closure using a Gore Septal Occluder provide clinical benefit in a patient with single ventricular physiology and severe aortic regurgitation?
Case Report (n=1)
Does transcatheter native aortic valve closure using a Gore Septal Occluder provide clinical benefit in a patient with single ventricular physiology and severe aortic regurgitation?
Transcatheter closure of the native aortic valve using a septal occluder may be a feasible rescue therapy for severe aortic regurgitation in patients with single ventricle physiology.
Answers are grounded in this paper and cite their sources.
May offer rescue therapy for severe AR in single-ventricle physiology; hypothesis-generating and requires prospective validation.
Semilunar valve regurgitation in single ventricular physiology is rare but portends a poor prognosis. Medical therapy is often ineffective particularly in the context of structural valve abnormality, and surgical valve repair or replacement can be associated with poor outcomes. We report an innovative use of a highly occlusive and conformable Gore Septal Occluder for transcatheter treatment of severe native aortic regurgitation in a symptomatic patient with hypoplastic left heart syndrome and severe systemic right ventricular dysfunction, resulting in safe and complete occlusion of the aortic regurgitant orifice and clinical benefit.
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Kang et al. (2024) conducted a case report in Severe aortic regurgitation in single ventricular physiology (n=1). Transcatheter native aortic valve closure using Gore Septal Occluder was evaluated on Occlusion of the aortic regurgitant orifice and clinical benefit. Transcatheter treatment using a Gore Septal Occluder resulted in safe and complete occlusion of the aortic regurgitant orifice and clinical benefit in a patient with severe aortic regurgitation.
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