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February 27, 2007Archives of Gynecology and ObstetricsOpen Access

Congenital cytomegalovirus infection in pregnancy: a case report of fetal death in a CMV-infected woman

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Key result

Maternal primary or recurrent congenital CMV infection can cause severe fetal disease and sudden intrauterine fetal death, as demonstrated by a stillbirth at 18 weeks gestation with massive CMV-placentitis.

Population

1 pregnant woman with congenital cytomegalovirus (CMV) infection

Design

Case_report

Authors

BKBernd KostLMU KlinikumIMIoannis MylonasFederation of Greek MaricultureRKRalph KästnerWalter Reed National Military Medical Center

Discussion

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Overview

Consider congenital CMV in unexplained stillbirth; extends sparse case reports but leaves open population-level implications.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 37-year-old pregnant woman who experienced a stillbirth in the 18th week of gestation due to congenital CMV infection.
O
Outcome
Fetal death (stillbirth)hard clinical

Highlights the possibility of primary or recurrent congenital CMV infection as a cause for sudden unknown congenital fetal death.

Limitations

  • Single case report
  • Exact time point of infection could not be determined due to lack of earlier serum samples

Cite This Study

Kost et al. (2007) conducted a case report in Congenital cytomegalovirus infection in pregnancy (n=1). Congenital cytomegalovirus (CMV) infection was evaluated on Intrauterine fetal death. Maternal primary or recurrent congenital CMV infection can cause severe fetal disease and sudden intrauterine fetal death, as demonstrated by a stillbirth at 18 weeks gestation with massive CMV-placentitis.

synapsesocial.com/papers/6ab78d1075407bc9b085a3cdhttps://doi.org/10.1007/s00404-007-0327-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Maternal antibodies against cytomegalovirus in pregnancy and the risk of fetal death and low birth weight2005 · 14 citations
  2. 2Passive Immunization During Pregnancy for Congenital Cytomegalovirus Infection2006 · 294 citations
  3. 3A prospective study of primary cytomegalovirus infection during pregnancy: final report1984 · 246 citations
  4. 4Intrauterine death and infections during pregnancy1995 · 30 citations
  5. 5Acute Respiratory Disease in Spain: Seven Years of Experience1990 · 55 citations