Key result
A 23-year-old woman with abnormal vaginal bleeding was diagnosed with a rare proximal-type epithelioid sarcoma confined to the uterine cervix after the mass recurred 2 months post-resection.
Case Report (n=1)
Proximal-type epithelioid sarcoma is an extremely rare but aggressive neoplasm that should be considered in the differential diagnosis of epithelioid tumors involving the female genital tract.
Rare PES case in female genital tract; leaves open diagnostic criteria and management for this aggressive sarcoma.
Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in older patients who present a more aggressive course. In the female genital tract, proximal-type epithelioid sarcoma (PES) mainly affects the vulva and is extremely uncommon in the uterus. To our knowledge, only a few cases of PES involving the cervix and uterine body have been previously reported in the literature. We report a 23-year-old woman who presented with abnormal vaginal bleeding. She was found to have a cervical mass, which was resected and diagnosed as a hemangioendothelioma. However, 2 months later, the mass recurred and the histopathological analysis at our institution demonstrated a PES confined to the uterine cervix. It is important to include this neoplasm in the differential diagnosis of epithelioid tumors that can involve the female genital tract because it has a significant impact on prognosis and treatment.
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Suarez-Zamora et al. (2017) conducted a case report in Proximal-type epithelioid sarcoma of the uterine cervix (n=1). Tumor resection and histopathological analysis was evaluated on Diagnosis and recurrence of cervical mass. A 23-year-old woman with abnormal vaginal bleeding was diagnosed with a rare proximal-type epithelioid sarcoma confined to the uterine cervix after the mass recurred 2 months post-resection.
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