Key result
A mathematical model of microvascular network blood flow predicted temporal variations in discharge hematocrit and blood velocity due to hemodynamic factors alone.
Population
Mathematical model applied to four rat mesenteric networks
Design
Preclinical
Authors
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Model predictions indicate hemodynamic factors alone can drive microvascular variations; leaves open in vivo validation and clinical translation.
A mathematical model demonstrates that temporal fluctuations in microvascular blood flow parameters can be caused solely by hemodynamic and hemorheological mechanisms.
Kiani et al. (1994) studied Microvascular blood flow (n=4). Mathematical model of microvascular network blood flow was evaluated on Temporal variations in discharge hematocrit (Hctd) and blood velocity. A mathematical model of microvascular network blood flow predicted temporal variations in discharge hematocrit and blood velocity due to hemodynamic factors alone.
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