Key result
Cryoablation with LAA clipping linked to better long-term sinus rhythm maintenance than RFA.
Why the study?
The effectiveness of surgical treatments for atrial fibrillation in patients with rheumatic mitral valve disease, specifically comparing cryoablation and radiofrequency ablation, was evaluated for the first time in Kazakhstan.
Does cryoablation with left atrial appendage clipping improve long-term maintenance of sinus rhythm compared to radiofrequency ablation with left atrial appendage suturing in patients with atrial fibrillation and rheumatic mitral valve disease?
Cohort (n=100)
Does cryoablation with left atrial appendage clipping improve long-term maintenance of sinus rhythm compared to radiofrequency ablation with left atrial appendage suturing in patients with atrial fibrillation and rheumatic mitral valve disease?
Cryoablation with left atrial appendage clipping may offer advantages over radiofrequency ablation with suturing for maintaining sinus rhythm and improving cardiac remodeling in patients undergoing surgery for rheumatic mitral valve disease and atrial fibrillation.
Answers are grounded in this paper and cite their sources.
May support cryoablation with clipping in rheumatic mitral surgery; leaves open need for RCTs to confirm benefit.
Background. This study presents the results of a clinical trial evaluating the effectiveness of surgical treatments for atrial fibrillation in patients with rheumatic mitral valve disease. Special attention is given to the comparison of cryoablation and radiofrequency ablation, two methods used in conjunction with mitral valve surgeries. The results indicate that cryoablation, a method first used in Kazakhstan, has long-term advantages for restoring sinus rhythm and cardiac remodeling, thereby improving patients' quality of life. Materials and Methods. The study was conducted at the period from January 2020 to March 2024 through a retrospective analysis of data from patients with atrial fibrillation and rheumatic mitral valve disease who underwent surgical treatment using one of two methods: Cryoablation with left atrial appendage clipping (Group I) – 50 patients; Radiofrequency ablation with left atrial appendage suturing (Group II) – 50 patients. Results. According to the conducted research, both cryoablation and radiofrequency ablation are highly effective in restoring sinus rhythm in patients with atrial fibrillation and rheumatic mitral valve disease. Cryoablation, a procedure that was used for the first time in Kazakhstan, demonstrated significant advantages in the long-term maintenance of sinus rhythm and improvement in heart remodeling parameters, such as left atrial volume. This has enhanced the quality of life for patients. Conclusions. There is a need for the widespread implementation of innovative treatments for atrial fibrillation, such as cryoablation, as surgical procedures are more effective and patients with severe cardiovascular diseases have better outcomes.
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Nurbay et al. (2024) conducted a cohort in Atrial fibrillation and rheumatic mitral valve disease (n=100). Cryoablation with left atrial appendage clipping vs. Radiofrequency ablation with left atrial appendage suturing was evaluated on Restoration of sinus rhythm and cardiac remodeling. Cryoablation with left atrial appendage clipping demonstrated significant advantages over radiofrequency ablation in long-term maintenance of sinus rhythm and improvement in left atrial volume.
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