Key result
Viroporins emerge as multifunctional viral targets for novel antiviral drugs and vaccine development.
Why the study?
Viroporins have multiple functions beyond cell membrane permeabilization that are important for viral progeny production and other viral processes.
This paper reviews the structures and functions of viroporins in viral processes.
Viroporins may guide future antiviral and vaccine strategies; leaves open clinical efficacy pending targeted trials.
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Nieva et al. (2015) conducted an editorial in Viral infections. Viroporins are multifaceted viral proteins that not only form transmembrane pores but also interact with viral and cellular proteins, presenting potential targets for antiviral drugs and vaccines.
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