Laser-Assisted Drug Delivery in Early Post-Burn Hypertrophic Scars: Review Article

Hypertrophic scars and keloids arise from an excessivehealing process and frequently cause considerable distress topatients. Fractional ablative lasers generate tiny channels inthe skin and penetrate scar tissue, prompting a natural regenerationreaction in the damaged areas.Laser-assisted drug delivery (LADD) is a promising therapeutictechnique that involves the direct application of drugsthat alter scars within the scar tissue via small channels.Burn injuries stem from numerous etiologies, with hot liquids,solids, and flames being the most common culprits. Theseinjuries pose a significant source of morbidity and can impacton a patient’s quality of life, psychosocial well-being, andsocioeconomic burden. While advances in burn managementhave reduced mortality rates, they have also led to a growingnumber of patients experiencing sequelae, notably hypertrophicscars (HTSs).An overly accelerated healing process might result in hypertrophicscars and keloids, which can sometimes cause significantpatient issues. One cutting-edge technique for accuratelydistributing medications under the skin is laser-assisted drugdelivery, or LADD. LADD has proven to be quite successfulin treating burn injuries and scarring. They enable a speedyrecovery, are minimally intrusive, and have a low risk of adverseconsequences. Consequently, they are incorporated intocertain therapy protocols with other conservative and surgicalmethods, which can be quite effective but also have a greaterlikelihood of complications.