75906 Clinical Profile of Adult Patients with Erythromelalgia

Erythromelalgia is a rare, inherited or acquired disorder, characterized by episodes of pain, warmth, and erythema primarily in the extremities. Though reviews on erythromelalgia have been previously published, there is a lack of patient-level data on the presentation among adults. Through a retrospective chart review, we aimed to characterize the clinical profiles of adult patients with erythromelalgia who presented to the University of Pennsylvania’s Dermatology Clinic from 2022 to 2025. Of the 63 patients identified, most were female (76.2%), White (84.1%), and non-Hispanic (92.1%).