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Endovascular repair of primary coarctation in adults achieved a 50% increase in aortic diameter with an insignificant pressure gradient, though long-term equivalence to surgery remains undetermined.
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Endovascular repair of primary coarctation in adults is effective in the short-to-mid term, but long-term outcomes regarding hypertension relief compared to surgery remain uncertain.
Wheatley et al. [1] report a successful series of angioplasty and stenting of primary coarctation in adults. They achieved an excellent technical result with a 50% increase of the aortic diameter, and an insignificant post-procedural pressure gradient. They did not encounter complications. They carefully selected adult patients with a primary coarctation. These patients have a virgin aorta at the coarctation site lacking calcified or fibrotic scar tissue, large access arteries and they are commonly lacking associated aortic pathologies. Proper indications, experience in endovascular procedures and great care with balloon dilation and stenting are key factors in achieving such results. The study demonstrates, along with other published series within the past few years, that an endovascular treatment of coarctation in selected patients is effective in the immediate and midterm outcome with a low complication rate. False aneurysms, dissections and restenosis account for 10–17% of the most commonly associated complications. Endoluminal stretching of the coarctation can cause disruption of the aortic wall weakened by cystic medial necrosis. If the morphology of the coarctation is at risk of such a complication, the use of a stent graft or covered stent is preferred to a bare stent, to seal the aortic tear. The stent graft is initially placed at the coarctation, and then, if necessary, a subsequent dilation can be performed safely and more vigorously within the stent graft. Alternatively, balloon expandable bare stents can be used. By expanding these stents only moderately, upsizing remains possible should a restenosis be discovered. These days the endovascular armamentarium is ample offering treatment in primary coarctation as well as in complications of a former endovascular or surgical repair. Endovascular interventions are associated with less postoperative pain and avoidance of ‘surgical morbidity’. Given these factors, why would a patient elect for surgery? However, the principal reason for intervening in patients with coarcation is to relieve hypertension and to palliate premature coronary and cerebrovascular disease. Wheatley et al. did not report data about hypertension, although it is recommended to perform supine and exercise blood measurements at the time of the intervention as well as during follow-up. Coarctation repair results in immediate improvement of hypertension in about 60% of cases and with similar results for endovascular and surgical groups [2]. It becomes less effective with increasing age at repair, and, from this point of view, the adult subgroup is probably not the one who will benefit most. Actually, the long-term outcome over decades is known only after surgery with a durable cure rate between 50% and 60%. The equivalence of the endovascular repair in the long term has not yet been determined; however, even if it turns out less favourable, who would opt for surgery?
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Bettina Marty (2010) conducted an editorial in Primary coarctation in adults. Endovascular repair (angioplasty and stenting) vs. Surgery was evaluated. Endovascular repair of primary coarctation in adults achieved a 50% increase in aortic diameter with an insignificant pressure gradient, though long-term equivalence to surgery remains undetermined.
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