Key result
NAFLD is not invariably associated with metabolic syndrome, and mechanisms other than insulin resistance, such as increased hemoglobin, may contribute to its development.
Population
Patients with nonalcoholic fatty liver disease (NAFLD) in the absence of metabolic syndrome (MetS)
Design
Review
Authors
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May broaden NAFLD evaluation beyond metabolic syndrome; leaves open hemoglobin and other non-insulin resistance pathways for investigation.
NAFLD can develop without metabolic syndrome, suggesting alternative pathogenetic mechanisms like increased hemoglobin that may require different targeted interventions.
Yusuf Nadir Yilmaz (2012) conducted a review in Nonalcoholic fatty liver disease (NAFLD). Increased hemoglobin was evaluated. NAFLD is not invariably associated with metabolic syndrome, and mechanisms other than insulin resistance, such as increased hemoglobin, may contribute to its development.
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