Key result
Early arterial reconstruction and interdisciplinary care improve survival and preserve organ function in middle aortic syndrome.
Why the study?
Middle aortic syndrome is increasingly implicated in primary hypertension and its visceral manifestations may be underrecognized, requiring review of pathogenesis and management.
Early intervention with interdisciplinary medical management and invasive arterial reconstruction in Middle Aortic Syndrome can preserve end-organ function and improve survival.
May support early intervention in middle aortic syndrome; leaves open need for prospective validation.
Middle aortic syndrome (MAS) is characterized by severe narrowing of the abdominal aorta, frequently involving the great abdominal vessels. Although increasingly implicated in primary hypertension, up to one-third of cases affect the mesenteric vasculature, and the resultant manifestations may be underrecognized. Early intervention with interdisciplinary medical management and invasive arterial reconstruction affords preservation of end-organ function and improvement in patient survival. This article reviews the embryology of the thoracoabdominal aorta and major abdominal arteries, as well as the pathogenesis, clinical manifestations, and management of the nonatherosclerotic abdominal coarctation otherwise known as MAS.
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Morray et al. (2018) conducted a review in Middle aortic syndrome. Interdisciplinary medical management and invasive arterial reconstruction was evaluated. Early intervention with interdisciplinary medical management and invasive arterial reconstruction for middle aortic syndrome affords preservation of end-organ function and improves patient survival.
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