Answers are grounded in this paper and cite their sources.
Skin biopsies of three patients with Lafora disease (clinically typical and proven by liver biopsy) showed PAS-positive inclusions in numerous peripheral cells of eccrine sweat ducts. By electronmicroscopy, the inclusions consisted of polyglucosan-type material; they were not bounded by a membrane. Skin biopsy should be a convenient method of diagnosing Lafora disease.
No takes yet. Share an insight, caveat, or question.
Carpenter et al. (1981) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: