Key result
Hot balloon ablation yields ~92% AF freedom at 11 months following complete posterior LA isolation.
Why the study?
Atrial fibrillation originates mostly from pulmonary vein foci or non-PV foci in the posterior left atrium, and the feasibility and safety of a novel radiofrequency hot balloon catheter for isolating these areas needed evaluation.
Does a radiofrequency hot balloon catheter safely and effectively isolate the posterior LA and PVs in patients with drug-resistant atrial fibrillation?
Population
100 consecutive patients with drug-resistant atrial fibrillation (63 paroxysmal, 37 persistent)
Comparison
Radiofrequency hot balloon catheter for isolation of posterior LA and all PVs
Design
Feasibility study
Follow-up
11.0+/-4.8 months
Authors
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May support hot balloon ablation for posterior LA isolation in AF; hypothesis-generating pending randomized confirmation.
Does a radiofrequency hot balloon catheter safely and effectively isolate the posterior LA and PVs in patients with drug-resistant atrial fibrillation?
The radiofrequency hot balloon catheter is a feasible and safe method for achieving complete isolation of the posterior LA and PVs, with high rates of freedom from AF at 11 months.
Sohara et al. (2009) studied Drug-resistant atrial fibrillation (n=100). Radiofrequency hot balloon catheter was evaluated on Freedom from atrial fibrillation without antiarrhythmic drugs. Radiofrequency hot balloon catheter ablation achieved complete isolation of the posterior LA and PVs in 100% of cases, with 92% of patients free from atrial fibrillation at 11 months.
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