Key result
Higher preoperative creatinine linked to ~5% higher risk of postoperative renal dysfunction after cardiac surgery.
Why the study?
Renal dysfunction significantly affects outcomes after cardiac surgery using cardiopulmonary bypass, with higher incidence of renal failure and diabetes in Saudi Arabia compared to western populations.
Does preoperative creatinine predict postoperative renal dysfunction in patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
244 adult patients undergoing cardiac surgery using cardiopulmonary bypass at King Faisal Cardiac Center, Saudi Arabia
Comparison
Not applicable; observational assessment of renal outcomes post-cardiac surgery
Design
Retrospective cohort study using non-probability consecutive sampling
Follow-up
30 days
Authors
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May support preoperative risk stratification; leaves open whether targeted interventions improve renal outcomes after cardiac surgery.
Cohort (n=244)
No
Does preoperative creatinine predict postoperative renal dysfunction in patients undergoing cardiac surgery with cardiopulmonary bypass?
Odds Ratio: 1.05 (95% CI 1.031–1.064)
p-value: p=0.0001
Preoperative creatinine is a significant predictor of postoperative renal dysfunction in patients undergoing cardiac surgery with cardiopulmonary bypass.
Alqarni et al. (2020) conducted a cohort in Cardiac surgery (n=244). Preoperative creatinine level vs. Lower preoperative creatinine level was evaluated on Postoperative renal dysfunction (OR 1.05, 95% CI 1.031-1.064, p=0.0001). Higher preoperative creatinine levels significantly predicted the development of postoperative renal dysfunction in patients undergoing cardiac surgery (OR 1.05).
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