Key result
Posterior ventricular anchoring neochordal repair eliminates MR in ~93% of patients.
Why the study?
Mitral valve repair techniques for degenerative disease often require complex leaflet resection or neochordal construction with limitations such as impaired leaflet mobility and systolic anterior motion.
Does posterior ventricular anchoring neochordal repair reduce mitral regurgitation in patients with degenerative mitral regurgitation?
Observational (n=54)
Does posterior ventricular anchoring neochordal repair reduce mitral regurgitation in patients with degenerative mitral regurgitation?
A novel posterior ventricular anchoring neochordal repair technique effectively reduces degenerative mitral regurgitation without the need for leaflet resection or precise neochordal measurement.
May support resection-free repair in degenerative MR; leaves open durability and randomized validation.
OBJECTIVES: Mitral valve repair techniques for degenerative disease typically entail leaflet resection or neochordal construction, which may require extensive resection, leaflet detachment/reattachment, reliance on diseased native chords or precise neochordal measuring. Occasionally, impaired leaflet mobility, reduced coaptation surface and systolic anterior motion (SAM) may result. We describe a novel technique for addressing posterior leaflet prolapse/flail, which both simplifies repair and addresses these issues. METHODS: Fifty-four patients (age 62 ± 11 years) with degenerative MR underwent this new repair, 36 of whom minimally-invasively. A CV5 Gore-Tex suture was placed into the posterior left ventricular myocardium underneath the prolapsing segment as an anchor. This suture was then used to imbricate a portion of the prolapsed segment into the ventricle, creating a smooth, broad, non-prolapsed coapting surface on a leaflet with preserved mobility, additional neochordal support and posteriorly positioned enough to preclude SAM. RESULTS: Repair was successful in all patients. The mean MR grade was reduced from +3.8 to +0.1 with 50 of 54 patients having zero MR and 4 of the 54 having trace or mild MR. All patients had proper antero-posterior location of the coaptation line of a mean length of 10.2 mm, and preserved posterior leaflet mobility. No patients had SAM or mitral stenosis. All patients were discharged and are currently doing well. CONCLUSION: This new technique facilitated efficient single-suture repair of the prolapsed posterior leaflet mitral regurgitation without the need for resection or sliding annuloplasty. It precluded the need for precise neochordal measurement and preserved the leaflet coaptation surface.
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Do et al. (2013) conducted an observational in Degenerative mitral regurgitation (n=54). Posterior ventricular anchoring neochordal repair was evaluated on Zero mitral regurgitation. Posterior ventricular anchoring neochordal repair successfully reduced mean mitral regurgitation grade from +3.8 to +0.1, with 50 of 54 patients (92.6%) achieving zero MR.
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