Key result
Neochordal repair using the folding leaflet technique in 68 patients with complex mitral valve prolapse yielded 1 in-hospital death and no cases of Grade 3 or 4 mitral regurgitation at follow-up.
Why the study?
Does the 'Folding Leaflet' technique for neochordal repair improve mitral regurgitation in patients with complex mitral valve prolapse?
Observational (n=68)
Does the 'Folding Leaflet' technique for neochordal repair improve mitral regurgitation in patients with complex mitral valve prolapse?
The 'Folding Leaflet' technique for neochordal repair in complex degenerative mitral regurgitation yields excellent early and mid-term echocardiographic outcomes with no severe residual regurgitation.
Supports folding leaflet neochordal repair in complex prolapse; leaves open need for randomized comparisons to standard techniques.
OBJECTIVES: Neochordal repair is particularly limited in case of large prolapse with absence of a reference point on a nearby segment. Our aim was to overcome these limitations by means of a simple technique: the 'Folding Leaflet'. METHODS: Ninety-six patients underwent this technique between January 2009 and August 2012 from a global mitral valve (MV) repair group of 384 patients. A subgroup of 68 patients with complex lesions, bileaflet, commissural or multisegment prolapse, was selected. These more challenging patients were considered as the study group in order to assess the efficacy of our technique. The neochordae were fixed to the papillary muscle with a simple stitch and then were passed through the free margin of the prolapsing leaflet. Free-edge remodelling was achieved weaving this suture and surpassing the coaptation line. Then, the leaflet was folded and its free margin was temporarily approximated edge-to-edge to the adjacent annulus. This was used as the reference point while the neochordae were tied without the need for adjacent healthy chordae or use of callipers. Complete echocardiographic follow-up was obtained at 6-month intervals. RESULTS: All patients had ≥ 2 prolapsed segments: posterior leaflet (40 patients), anterior leaflet (13 patients) or both leaflets (15 patients). Annuloplasty was routinely used and the mean number of neochordae per patient was 4.1 ± 2.2 (2-13). Mean follow-up was 28 ± 14 months (5-49 months). There was only one in-hospital death. Another patient died by pneumoniae (15th postoperative month). At the first-month follow-up, 51 patients had no mitral regurgitation (MR) and 16 patients had Grade 1 MR. Only 1 patient had more than mild regurgitation at the 6-month follow-up. There was no evidence of Grade 3 or 4 MR in any patient. At the 2-year follow-up, 34 patients remained with no MR or trace MR and 7 patients had Grade 1 MR. CONCLUSIONS: MV repair for complex degenerative MR using this technique of neochordal repair results in excellent early and mid-term outcomes. This technique facilitates the extensive use of neochordae in case of large areas of prolapse.
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Fúster et al. (2014) conducted an observational in Complex mitral valve prolapse (n=68). Folding leaflet technique for neochordal repair was evaluated on Early and mid-term outcomes including mortality and mitral regurgitation grade. Neochordal repair using the folding leaflet technique in 68 patients with complex mitral valve prolapse yielded 1 in-hospital death and no cases of Grade 3 or 4 mitral regurgitation at follow-up.
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