Key result
Oral and subcutaneous inoculation of bovine enteroviruses in colostrum-deprived calves resulted in 50% mortality, comparable to the 52.9% mortality observed in uninoculated controls.
Population
1-day-old to 8-week-old calves and fetuses aborted at 4 months or more of gestation
Comparison
Oral and subcutaneous inoculation of bovine… vs Uninoculated calves
Design
Preclinical
Authors
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May induce leukopenia and fever in calves without excess mortality; leaves open true pathogenicity and supports further serotype studies.
Absolute Event Rate: 50% vs 52.9%
Bovine enterovirus inoculation in calves causes leukopenia and fever, and evidence suggests in utero infection may contribute to early death or reduced resistance to bacterial infection.
Dunne et al. (1974) studied Bovine enterovirus infection. Bovine enterovirus inoculation vs. Uninoculated calves was evaluated on Mortality in colostrum-deprived calves. Oral and subcutaneous inoculation of bovine enteroviruses in colostrum-deprived calves resulted in 50% mortality, comparable to the 52.9% mortality observed in uninoculated controls.
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