January 18, 2011Veterinary PathologyOpen Access

Pathogenesis of a Bovine Enterovirus-1 Isolate in Experimentally Infected Calves

Q: What is the clinical evidence from this study?

Study design: Other. Population: Bovine enterovirus-1 (BEV-1) infection. Intervention: Experimental inoculation with the Oklahoma isolate of BEV-1 vs. None. Primary outcome: Virus localization and lesion development.

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Key result

Experimental inoculation of young calves with BEV-1 led to virus localization in the gastrointestinal tract, brain, and heart, without acute clinical signs.

Population

Calves experimentally inoculated with the Oklahoma isolate of Bovine enterovirus-1 (BEV-1)

Design

Preclinical

Authors

UBUriel Blas‐MachadoUniversity of Georgia JSJeremiah T. SalikiOklahoma State University SSSusan SánchezGeorgia College & State University

Discussion

Member takes

Implication

May link BEV-1 to subclinical bovine cardiac pathology; leaves open its role in arteritis or encephalitis.

Structured PICO

Population

Young calves experimentally inoculated with the Oklahoma isolate of BEV-1 to study the pathogenesis of acute infection.

Intervention

Experimental inoculation with the Oklahoma isolate of Bovine enterovirus-1 (BEV-1)

Outcome

Pathogenesis, virus localization, and potential development of lesions in the brain and heartsurrogate

Experimental infection of calves with BEV-1 demonstrates viral localization in enteric, neural, and cardiac tissues, suggesting a potential role in encephalitis and coronary arteritis despite the absence of acute clinical signs.

Limitations

lack of an effective control group

Cite This Study

Blas‐Machado et al. (2011) studied Bovine enterovirus-1 (BEV-1) infection. Experimental inoculation with the Oklahoma isolate of BEV-1 vs. None was evaluated on Virus localization and lesion development. Experimental inoculation of young calves with BEV-1 led to virus localization in the gastrointestinal tract, brain, and heart, without acute clinical signs.

synapsesocial.com/papers/6a6f580cf44fa9f079dcc511 https://doi.org/10.1177/0300985810395728

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January 18, 2011Veterinary PathologyOpen Access

Pathogenesis of a Bovine Enterovirus-1 Isolate in Experimentally Infected Calves

View Full Paper

Ask AI

Bookmark

Key result

Experimental inoculation of young calves with BEV-1 led to virus localization in the gastrointestinal tract, brain, and heart, without acute clinical signs.

Population

Calves experimentally inoculated with the Oklahoma isolate of Bovine enterovirus-1 (BEV-1)

Design

Preclinical

Authors

UBUriel Blas‐MachadoUniversity of Georgia JSJeremiah T. SalikiOklahoma State University SSSusan SánchezGeorgia College & State University

Discussion

Member takes

Implication

May link BEV-1 to subclinical bovine cardiac pathology; leaves open its role in arteritis or encephalitis.

Structured PICO

Population

Young calves experimentally inoculated with the Oklahoma isolate of BEV-1 to study the pathogenesis of acute infection.

Intervention

Experimental inoculation with the Oklahoma isolate of Bovine enterovirus-1 (BEV-1)

Outcome

Pathogenesis, virus localization, and potential development of lesions in the brain and heartsurrogate

Limitations

lack of an effective control group

Cite This Study

synapsesocial.com/papers/6a6f580cf44fa9f079dcc511 https://doi.org/10.1177/0300985810395728

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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