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May 1, 1974Journal of General Virology

Bovine Enterovirus-1: characterization, Replication and Cytopathogenic Effects

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Population

Cells infected with bovine enterovirus-1 (BEV-1)

Comparison

Bovine enterovirus-1 (BEV-1) infection vs Uninfected cells

Design

Preclinical

Authors

MTMichael W. TaylorUniversity of AucklandRSR. SuUniversity of Maryland, College ParkBCB. Cordell-StewartUniversity of California, San Francisco

Discussion

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Implication

BEV-1 properties support its use as a picornavirus model; leaves open relevance to bovine pathogenesis or zoonotic risk.

Structured PICO

P
Population
Cells infected with bovine enterovirus-1 (BEV-1)
I
Intervention
Bovine enterovirus-1 (BEV-1) infection
C
Comparator
Uninfected cells (implied for normal protein synthesis levels)
O
Outcome
Viral growth cycle, stability, and cytopathogenic effects

Bovine enterovirus-1 is a highly stable picornavirus characterized by a rapid replication cycle and early, profound inhibition of host cellular protein synthesis.

Cite This Study

Taylor et al. (1974) studied this question.

synapsesocial.com/papers/6a6f585335aa2c282ce0b99fhttps://doi.org/10.1099/0022-1317-23-2-173
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pathogenesis of a <i>Bovine Enterovirus-1</i> Isolate in Experimentally Infected Calves2011 · 53 citations
  2. 2Correlation Between Propagation of a Bovine Enterovirus and Development of Receptor-Like Material in Tissue Mince1969 · 7 citations
  3. 3Bovine Enterovirus CPE at Different Multiplicities of Infection in the Absence of Viral RNA Synthesis1979 · 4 citations
  4. 4Morphogenesis of Picornaviruses: Characterization and Assembly of Bovine Enterovirus Subviral Particles1976 · 22 citations
  5. 5Bovine enterovirus 2: complete genomic sequence and molecular modelling of a reference strain and a wild-type isolate from endemically infected US cattle2004 · 26 citations