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October 13, 2004Journal of General Virology

Bovine enterovirus 2: complete genomic sequence and molecular modelling of a reference strain and a wild-type isolate from endemically infected US cattle

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Population

Bovine enterovirus 2 strain PS87 and a wild-type isolate from an endemically infected herd in Maryland, USA

Comparison

Genomic sequencing and homology modelling vs BEV-1 strain (VG5-27) and other picornaviruses

Design

Preclinical

Authors

SGS. Denise GoensParkwood InstituteSBSebastian BoteroAZAdam ZemłaLawrence Livermore National Laboratory

Discussion

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Implication

Provides first BEV-2 sequences for genotyping and capsid modeling; leaves open relevance to clinical enterovirus surveillance or pathogenesis.

Structured PICO

P
Population
Bovine enterovirus 2 (BEV-2) strain PS87 and a wild-type isolate (Wye3A) from an endemically infected herd in Maryland, USA
I
Intervention
Genomic sequencing and homology modelling
C
Comparator
BEV-1 strain (VG5-27) and other picornaviruses
O
Outcome
Complete genomic sequence and molecular modelling of capsid proteinssurrogate

This first report of full-length sequences for BEV-2 provides useful information for genotyping enteroviruses and modelling enterovirus capsid structure.

Cite This Study

Goens et al. (2004) studied this question.

synapsesocial.com/papers/6a6f585335aa2c282ce0b99chttps://doi.org/10.1099/vir.0.80159-0
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bovine Enteroviruses in the Calf: An Attempt at Serologic, Biologic, and Pathologic Classification1974 · 35 citations
  2. 2Functional features of the bovine enterovirus 5′-non-translated region1999 · 45 citations
  3. 3Picornavirus uncoating2002 · 50 citations
  4. 4Tree View: An application to display phylogenetic trees on personal computers1996 · 10,249 citations