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July 11, 2025Veterinary SciencesOpen Access

Genomic Characterization of Two Bovine Enterovirus Strains Isolated from Newly Transported Cattle

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Key result

Genomic characterization identifies two novel bovine enterovirus strains from diarrheal cattle as the BEV-E4 subtype.

Population

Two novel Chinese bovine enterovirus strains isolated from newly transported cattle with diarrheal feces

Comparison

BEV-GX1901 vs BEV-GX1902

Design

Preclinical genomic and physicochemical characterization study

Authors

CWCuilan WuSZShuhong ZhongSFShi-Wen Feng

Discussion

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Overview

Extends BEV-E4 geographic range to China; leaves open pathogenicity and surveillance needs in cattle.

Structured PICO

P
Population
Two novel Chinese bovine enterovirus (BEV) strains (BEV-GX1901 and BEV-GX1902) isolated from newly transported cattle with diarrheal feces
I
Intervention
Genomic characterization and physical/chemical property analysis (CPE production, TCID50 measurement, trypsin sensitivity test, ether sensitivity test, chloroform sensitivity test, acid and alkali resistance test, and heat resistance test)
O
Outcome
Complete genome sequences and physical/chemical properties

The isolation and genomic characterization of two novel BEV-E4 strains from cattle in China provides insights into the distribution and properties of bovine enteroviruses.

Cite This Study

Wu et al. (2025) studied Bovine enterovirus infection. Isolation and genomic characterization of two novel Chinese bovine enterovirus strains (BEV-GX1901 and BEV-GX1902) from cattle with diarrhea revealed they belong to the BEV-E4 subtype.

synapsesocial.com/papers/6a0a1de830285ee4a1342effhttps://doi.org/10.3390/vetsci12070660
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Also Consider

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  1. 1Emergence of a Recombinant Bovine Enterovirus in China: Insights from Phylogenetic and Temporal Analysis2025 · 2 citations
  2. 2A novel enterovirus species identified from severe diarrheal goats2017 · 25 citations
  3. 3Survey of Bovine Enterovirus in Biological and Environmental Samples by a Highly Sensitive Real-Time Reverse Transcription-PCR2005 · 102 citations
  4. 4Serological Survey of Bovine Enterovirus Type 1 in Different Mammalian Species in Turkey2008 · 35 citations
  5. 5Molecular strategy for ‘serotyping’ of human enteroviruses2001 · 212 citations