Key result
Combining evidence from randomized controlled trials and real-world registry data provides the best approach for personalizing the treatment of patients with abdominal aortic aneurysms.
The author argues for combining RCT data with longitudinal registries and single-center data to provide real-world expectations for AAA patients.
Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands.
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Shah et al. (2018) conducted an editorial in Abdominal aortic aneurysm (AAA). Combining evidence from randomized controlled trials and real-world registry data provides the best approach for personalizing the treatment of patients with abdominal aortic aneurysms.
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