Key result
Optimal ICD programming reduces inappropriate and unnecessary shocks in primary prevention LV dysfunction.
Why the study?
Defibrillator shocks in primary prevention patients with left ventricular dysfunction are associated with morbidity and mortality, and their rate can be decreased with adequate device programming.
Do specific programming strategies (higher or later) reduce the rate of shocks in primary prevention patients with left ventricular dysfunction implanted with a defibrillator?
Do specific programming strategies (higher or later) reduce the rate of shocks in primary prevention patients with left ventricular dysfunction implanted with a defibrillator?
Adequate ICD programming strategies can reduce the rate of inappropriate and unnecessary shocks, which are associated with significant morbidity and mortality.
ICD shocks associate with higher mortality and morbidity; programming to minimize inappropriate shocks leaves survival benefit open.
Defibrillator shocks, appropriate or not, are associated with significant morbidity, as they decrease quality of life, can be involved in depression and anxiety, and are known to be proarrhythmic. Most recent data have even shown an association between shocks and overall mortality. As opposed to other defibrillator-related complications, the rate of inappropriate and unnecessary shocks can (and should) be decreased with adequate programming. This review focuses on the different programming strategies and tips available to reduce the rate of shocks in primary prevention patients with left ventricular dysfunction implanted with a defibrillator, as well as some of the manufacturers’ device specificities. Les chocs délivrés par les défibrillateurs automatiques implantables sont associés à une baisse de la qualité de vie des patients implantés (dépression, anxiété), et peuvent avoir un effet pro-arythmogène. Les études les plus récentes ont même montré un lien entre les chocs électriques internes et la mortalité totale. Contrairement aux autres complications, la fréquence de ces chocs peut (et doit) être diminuée grâce à une programmation adaptée. Cette revue de la littérature se focalise plus particulièrement sur les stratégies disponibles pour réduire la fréquence des chocs chez les patients implantés en prévention primaire pour une dysfonction systolique ventriculaire gauche, ainsi que sur les spécificités des appareils des différents constructeurs.
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Clémenty et al. (2014) conducted a review in Left ventricular dysfunction with primary prevention ICD. Adequate ICD programming strategies was evaluated. Adequate ICD programming strategies can reduce the rate of inappropriate and unnecessary shocks in primary prevention patients with left ventricular dysfunction.
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