Key result
Warfarin discontinuation in a mechanical aortic valve leads to coronary thromboembolism and acute MI.
Why the study?
Coronary artery embolism is an uncommon cause of acute myocardial infarction and its association with mechanical aortic valve patients discontinuing anticoagulation is important to highlight.
Population
24-year-old male with mechanical aortic valve presenting with acute inferoposterior myocardial infarction and cerebral TIA
Comparison
Discontinuation of warfarin therapy vs continued anticoagulation
Design
Case report
Authors
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Supports vigilance with anticoagulant interruption in mechanical valve patients; leaves open whether education interventions reduce events.
Case Report (n=1)
Discontinuation of anticoagulation in patients with mechanical heart valves can lead to severe thromboembolic events, including acute myocardial infarction and TIA, highlighting the need for continuous patient education.
Gholoobi et al. (2016) conducted a case report in Acute Myocardial Infarction and Coronary Embolism (n=1). Discontinuation of warfarin was evaluated on Coronary thromboembolism causing AMI and TIA. Discontinuation of warfarin in a 24-year-old male with a mechanical aortic valve resulted in coronary thromboembolism causing acute myocardial infarction and a transient ischemic attack.
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