March 14, 2012New England Journal of Medicine
Patent Foramen Ovale Closure — Closing the Door Except for Trials
Key result
Patent foramen ovale is a well-established cause of stroke but is also present in 25% of healthy people, often making it an incidental finding in patients presenting with stroke.
Why the study?
Should patent foramen ovale be closed in patients with stroke outside of clinical trials?
Population
Patients with stroke and patent foramen ovale
Design
Editorial
Authors
Discussion
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Member takes
Implication
The editorial emphasizes that patent foramen ovale closure for stroke prevention should primarily be conducted within the context of clinical trials due to the high background prevalence of PFO.
Structured PICO
Should patent foramen ovale be closed in patients with stroke outside of clinical trials?
P
Population
Patients with stroke and patent foramen ovale
I
Intervention
Patent foramen ovale closure devices
The editorial emphasizes that patent foramen ovale closure for stroke prevention should primarily be conducted within the context of clinical trials due to the high background prevalence of PFO.
Cite This Study
S. Claiborne Johnston (2012) conducted an editorial in Patent foramen ovale and stroke. Patent foramen ovale closure was evaluated. Patent foramen ovale is a well-established cause of stroke but is also present in 25% of healthy people, often making it an incidental finding in patients presenting with stroke.