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Implication for health policy/practice/research/medical education:Zolpidem is a nonspecific hypnotic drug that has antioxidant and neuroprotective properties.Cisplatin is mainly secreted through the kidneys, and its accumulation in tubular tuberculosis is more than 5 times greater than other tissues.Zolpidem exhibits this effect by reducing oxidative stress, increasing the activity of the antioxidant system, including superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX), and preventing apoptosis in renal cells.The present study has approved, the antioxidant effect of zolpidem on the improvement of the defect of antioxidant system of the kidney in nephrotoxicity.
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Hasanvand et al. (2018) studied this question.
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