Key result
Post-TAVI infective endocarditis occurs in ~2% of patients and carries 75% mortality.
Why the study?
Infective endocarditis after transcatheter aortic valve implantation may present with different clinical and echocardiographic characteristics that require description.
Observational (n=311)
No
Infective endocarditis following TAVI is a rare but highly lethal complication, with a 75% mortality rate in patients developing prosthetic valve endocarditis.
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High post-TAVI PVE mortality warrants surveillance caution; leaves open optimal prevention strategies pending prospective data.
INTRODUCTION: Infective endocarditis (IE) may take different faces in patients after transcatheter aortic valve implantation (TAVI). OBJECTIVES: The primary aim of this study was to describe echocardiographic and clinical characteristics of TAVI's patients suffered from IE. METHODS: In a single-center, retrospective study we analyzed 311 consecutive patients treated with TAVI for severe aortic stenosis between 2010 and 2018. RESULTS: According to modified Duke criteria, we confirmed IE in 2.2% of the cohort, however PVE of TAVI's valve in 1.2% only; rest of the group suffered from CDRiE and IE of the mitral valve. In PVE's group vegetations were localized inside the frame with or without bioprosthesis moderate stenosis or regurgitation. Only 1 pts developed significant TAVI's bioprosthesis' paravalvular leak. We observed no native aortic anulus involvement. Mortality rate in the PVE-TAVI's group was 75% regardless of the type of treatment. CONCLUSIONS: The above findings show that IE following TAVI is a serious complication and various scenarios (also CDRiE and native valve IE) should be considered.
Ścisło et al. (2019) conducted an observational in Severe aortic stenosis (n=311). Transcatheter aortic valve implantation (TAVI) was evaluated on Infective endocarditis (IE). Infective endocarditis occurred in 2.2% of patients after TAVI, with prosthetic valve endocarditis in 1.2% and a 75% mortality rate in the PVE-TAVI group.